Instruments

Chiralraman 2x : spectrometer SCP – ROA
(Scattered Circular Polarisation - Raman Optical Activity)

This spectrometer measures the vibrational raman optical activity spectra, generated by a 532 nm laser excitation, of chiral molecules or its secondary structures in liquid phase, water or in organic solvents from 100 to 2550 cm-1. It permits, for example, to determine the absolute configuration of a chiral molecule, and its conformations, by comparison with theoretical calculation, or also, to follow the handedness of nanometrical helices as bigemini tartrates.

PM-IRRAS:
Polarization modulation ‐ infrared reflection ‐ adsorption spectroscopy

FTIR spectrometer “Nexus 670” (Thermo Optek) : ATR, PM-IRRAS and PM-IRLD measurements

• Spectral range 7800-600 cm-1
• Detector: MCT (7800-650 cm-1)
• Beamsplitters: Ge-KBr (7800-350 cm-1)
• Source: mid-infrared
• Spectral resolution: up to 0.125 cm-1
• Dynamic alignment
• Coupled to PM-IRRAS home made system (4000-850 cm-1)
• Coupled to PM-IRLD home made system (4000-850 cm-1)

Applications:

• ATR experiments in the mid-infrared using Golden gate and Silver gate accessories
• PM-IRRAS experiments to characterize ultra thin films deposited onto metallic substrates and SAMs grafted onto SiO2/Gold substrates
• PM-IRLD experiments to determine linear dichroism of thin films (photoinduced orientation in azopolymer films, molecular orientation in stretched polymers ...).

PM-VCD:
Polarization modulation - Vibrational Circular Dichroism

FTIR spectrometer “Nexus 670” (Thermo Optek) : Standard and VCD measurements

• Spectral range 7800-600 cm-1
• Detector: DLaTGS with KBr (12500-350 cm-1)
• Beamsplitters: Ge-KBr (7800-350 cm-1)
• Source: mid-infrared
• Spectral resolution: up to 0.125 cm-1
• Dynamic alignment
• Coupled to VCD home made system (4000-850 cm-1)

Applications:

• Standard experiments on solid or liquid samples in the mid-infrared
• VCD experiments to determine the absolute configuration and/or conformation of chiral molecules in solution

Solution and solid-state NMR spectroscopy

Bruker NMR spectrometers: 300MHz, 400MHz, 500MHz, 600MHz, 700MHz and 800MHz.

• Spectrometer 800 MHz Bruker: Cryoprobe TCI 1H-13C/15N/2H, CPMAS 4 mm 1H/BB, CPMAS 3.2 mm 1H/13C/15N
• Spectrometer 700 MHz Bruker: TXI (1H, 13C, 15N, 2H), HRMAS (1H, 13C, 15N, 2H), CPMAS 4mm (1H, 2H, 31P), E-free CPMAS 4mm (15N – 31P, 1H)
• Spectrometer 600MHz Bruker: CPMAS 1.3mm (1H, 13C, 15N, 2H), CPMAS 4mm (1H, 13C, 15N), CPMAS 3.2mm (1H, 13C, 15N), CPMAS 4mm (1H, X)
• Spectrometer 500 MHz Bruker: HRMAS (1H, 13C, 2H), CPMAS 4mm (1H, X, Y), CPMAS 2.5mm (1H, X, Y), CPMAS 4mm (1H, X)
• Spectrometer 400 MHz Bruker: QNP (13C-31P-19F, 1H, 2H), BBI (15N-31P, 1H, 2H)
• Spectrometer 300 MHz Bruker: CPMAS 4mm (1H, X, Y), CPMAS 4mm (1H, X, Y)

Applications:

• Solid-state NMR of supramolecular assemblies, ranging from small supramolecular systems to large supramolecular protein complexes.
• Solution NMR analysis: structure determination and relaxation studies.

CPL-300:
Circularly Polarized Luminescence Spectrometer

• Light source: 150W Ozon-free air-cooled Xe lamp
• Detector: Head-on photomultiplier tube (PMT)
• Modulator: Piezoelastic modulator
• Electrical system: Lock-in amplifier
• Monochromator: Double prism monochromators for both Ex and Em parts
• Detection range: 250-850 nm (400-1100 nm with near IR detector)
• Stray light: 0.001% or less
• Temperature control: 0-100˚C

Applications:

• CPL spectral measurements for liquid samples such as solutions and suspensions
• CPL spectral measurements for solid samples (transmission) such as films